Nanoscopy is a field of microscopy that focuses on imaging and studying structures and processes at the nanoscale, typically below the diffraction limit of light. It encompasses various techniques ...

Pushing optical imaging below the diffraction limit usually requires complicated illumination schemes and still suffers from weak, unstable signals ...

What is Single-Molecule Localization Microscopy? Single-molecule localization microscopy (SMLM) is a super-resolution imaging technique that enables the visualization of biological structures and ...

I get to blow my own horn about some of our research. We have some calculations that show that it might be possible to get sub-diffraction-limited resolution images from a CARS microscope, which could ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

Fluorescence light microscopy techniques offer several advantages when imaging biological samples, including high image contrast, good labeling specificity, multicolor, and three dimensional (3D) ...

It’s relatively easy to understand how optical microscopes work at low magnifications: one lens magnifies an image, the next magnifies the already-magnified image, and so on until it reaches the eye ...